By Philipp Dahm, Roger Dmochowski
This distinctive publication presents up to date details at the appropriateness of either scientific and surgical procedure strategies for a wide spectrum of urological stipulations in response to the present most sensible evidence.
Written via a global group of authors that stand out via their area of expertise services and management in training evidence-based urology, this e-book presents functional concepts for the care of person sufferers. each one bankruptcy addresses a sequence of targeted medical questions which are addressed in a scientific style, together with a entire literature seek, a score of the standard of facts, and an overview of ratio of profit and damage of a given remedy option.
Evidence-Based Urology is a useful resource of evidence-based info distilled into tips for scientific perform
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This certain e-book offers updated info at the appropriateness of either clinical and surgical procedure suggestions for a wide spectrum of urological stipulations in response to the present top proof. Written by means of a world staff of authors that stand out via their strong point services and management in working towards evidence-based urology, this ebook offers sensible strategies for the care of person sufferers.
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This may be a potential source of bias, if a surgeon consciously or subconsciously favors one procedure over 13 CHA PT ER 2 Clinical trials in urology another . One potential solution to this challenge is the concept introduced by Devereaux et al.  of “expertisebased” clinical trials, where a surgeon only performs one procedure in which he/she has special skill or experience. The comparison procedure would be performed by a different surgical expert. In this manner, potential bias from unblinded surgeons would be minimized.
The randomization in RCTs is intended to protect against this problem. Blinding is another important component of RCTs. The strongest RCTs use a double-blind procedure in which neither clinicians nor patients know which treatment is being administered. Blinding is particularly important when the disorder under study is likely to manifest large placebo effects. Blinding is not always possible, however. For example, it is not possible to blind a surgeon to the type of surgery he or she is to perform or to blind a patient to the fact that she is to receive a pill rather than an intravesical treatment.
Conclusion Results of well-designed and executed RCTs provide the highest level of evidence for the practice of urology. Evidence suggests that the quality of reporting in urologic RCTs is at times suboptimal [20,22]. Therefore, the informed reader of the urological literature should be aware of the design and statistical elements which safeguard against bias and misleading results from trials. Ultimately, becoming an informed consumer of the urological literature should be the goal of every urologist aspiring to an evidence-based clinical practice.