By Roger S. Kirby
Written by means of Roger Kirby, An Atlas of Erectile disorder, moment variation provides clinicians with quick access to the knowledge they should comprehend the motives, pinpoint the analysis, and begin secure and potent remedy. Dr. Kirby explores the new, speedy adjustments within the figuring out of the pathophysiology and the administration algorithms concerning the main applicable and reasonable method of dealing with erectile disorder. The atlas comprises diagrams which are truly defined and simple to appreciate and amazing illustrations and colour images, which makes this atlas a must-read for an individual treating sufferers with struggling with erectile disorder.
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Additional info for An Atlas of Erectile Dysfunction
Both cAMP and cGMP lower intracellular calcium (Ca2+). In contrast, norepinephrine acts via the α-adrenoceptor. Activation of this G-protein-linked receptor stimulates production of inositol phosphate (IP3) by a phospholipase C (PLC)-dependent mechanism. IP3 acts to increase intracellular Ca2+, thereby inducing contraction of intracavernosal smooth muscle cells 44 Figure 18 Norepinephrine is released from dense-core vesicles in sympathetic nerve terminals within the corpora. Norepinephrine then diffuses across the synaptic gap to activate α-adrenoceptors located on the cavernosal smooth muscle cell membrane.
Qual Life Res 1996;5:443–9 Wespes E, Schulman CC. Venous leakage: surgical treatment of a curable cause of impotence. J Urol 1985; 133:796–8 Wespes E, Schulman C. Venous impotence: pathophysiology, diagnosis and treatment. J Urol 1993;149:1238–45 Wilson SK, Wahman GE, Lange JL. Eleven years’ experience with the inflatable penile prosthesis. J Urol 1988;139:951–2 Witherington R. Vacuum constriction device for management of erectile impotence. J Urol 1989;141:320–2 Zelefsky MJ, McKee AB, Lee H, Leibel SA.
In either case, correction may be achieved by excision of an elliptical portion of tissue (or a series of elliptical pieces) from the side opposite the curvature. This maneuver (see Figure 89), first described by Nesbit, usually leads to a good outcome, but is achieved at the cost of penile shortening (usually 2–3 cm). The plication technique (Figure 90) also results in loss of erectile length. To avoid this, other techniques have been described, including plaque incision (Figure 91) and excision (Figure 92), and grafting of the defect with a segment of vein or other material.