By Robert S. Tan
A whole reference on universal overall healthiness matters for the getting older man
The worldwide inhabitants is getting older, and this crucial textual content explores the typical wellbeing and fitness matters that accompany male getting older, really the consequences of declining testosterone degrees, or andropause. here's the 1st and simply booklet to comprehensively overview this subject.
Using a case-based strategy with assisting facts, the ebook examines therapy for the organic and physiological adjustments that stem from quite a lot of age-related difficulties linked to androgen deficiency. you'll examine such subject matters as erectile disorder, prostate melanoma, middle sickness, arthritis, osteoporosis, weight problems, development hormone substitute for getting older males, nutriceuticals, hypogonadism, and masses extra. Findings brought up from contemporary literature be sure trustworthy research in each bankruptcy, and a hundred charts and graphs make clear study and key points.
The medical implications of male getting older expand into many disciplines--orthopedics, urology, endocrinology, cardiology, and others. applicable remedy and care are an important. hugely informative and authoritative, this concise reference is a needs to for all practitioners treating the getting older male patient.
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Extra info for Aging men's health: a case-based approach
Researchers sometimes refer to it as a “testosterone storm” as most deaths in this male group come from motor vehicle accidents, followed by homicide, suicide, cancer, and drowning. After the age of 24 years, the difference between male and female mortality narrows until late middle age. qxd 14 10/2/05 2:39 pm Page 14 AGING-MEN’S HEALTH: A CASE-BASED APPROACH more men than women die, due mainly to heart disease, suicide, car accidents, and illnesses related to smoking and alcohol use. Heart disease kills 5 of every 1000 men in this age group.
Telomeres are synthesized by telomerase, a ribonucleoprotein reverse transcriptase enzyme that maintains the lengths of chromosomes. Loss of telomeres can lead to DNA damage. This association of telomere shortening and senescence in vitro has been established. Cells that have been supplied with an exogenous source of telomerase maintain a youthful state and proliferate indefinitely. clinical implications It is a notion that in normal human organs with a capacity for cell replacement, the telomere clock may allow enough divisions for normal growth, repair, and maintenance.
If the DNA repair process did not exist, scientists estimate that enough damage would accumulate in cells in 1 year to make them nonfunctional. Others believe that aging is caused by DNA damage through intrinsic mutations or other TABLE 2–1. 2 Adapted from Ivanova R, Henon N, Lepage V, et al. HLA-DR alleles display sex-dependent effects on survival and discriminate between individual and familial longevity. Hum Mol Genet 1998;7:187–194, with permission. qxd 16 10/2/05 2:39 pm Page 16 AGING-MEN’S HEALTH: A CASE-BASED APPROACH FIGURE 2–1.