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Download Adult Epilepsy by Gregory D. Cascino, Joseph I. Sirven PDF

By Gregory D. Cascino, Joseph I. Sirven

Designed to supply a accomplished yet obtainable advent to epilepsy and seizure problems, grownup Epilepsy presents state of the art details in a concise structure valuable to a large viewers, from neurology citizens to epilepsy fellows and practitioners. This illustrated advisor to the evaluation, prognosis, and therapy of epilepsy is a worthwhile source permitting clinicians to stick on best of the most recent suggestions for top perform.

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Extra resources for Adult Epilepsy

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2005) New onset geriatric epilepsy: a randomized study of gabapentin, lamotrigine and carbamazepine. Neurology, 64, 1868–1873. 27. C. (1985) Epilepsy after penetrating head injury. I. Clinical correlates; a report of the Vietnam head injury study. Neurology, 35, 1406–1414. 28. , and Corona, T. (2004) Calcific neurocysticercosis and epileptogenesis. Neurology, 62, 1934–1938. 26 EPIDEMIOLOGY OF SEIZURE DISORDERS 29. , Senocak, M. et al. (1999) Prevalence of epilepsy in Silivri, a rural area of Turkey.

2), which disrupts the ongoing EEG background activity. 2 Epileptiform sharp waves and spikes are transient waveforms that arise abruptly out of the EEG background activity. Sometimes, they occur repetitively in trains. The waveforms have more than one phase (usually two or three) and are characteristically asymmetrical. 3). 3 The duration of an epileptiform sharp wave is 70–200 ms and the duration of an epileptiform spike is less than 70 ms, although the distinction is of no clinical significance.

Because of the high sensitivity and high specificity of IEDs for seizure disorders and the high correlation of IED localization with seizure onset localization, IEDs can be interpreted as the electrophysiologic signature of the epileptogenic brain in the appropriate clinical setting. Evidence from simultaneous microelectrode and macroelectrode recordings suggests that IEDs represent the macroscopic field resulting from the summation of potentials from a population of pathologically synchronized bursting neurons.

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